의과대학 - 의과대학

  • 교수 바이러스학
  • 김균환
CV1

학력

  • 서울대학교 학사/석사
  • 연세대학교 박사

약력/경력

  • 브라운대학교 Post Doc
  • 건국대학교 의학전문대학원 교수

학술지 논문

  • (2024)  Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma.  DRUG RESISTANCE UPDATES.  73,  1
  • (2024)  PRKCSH contributes to TNFSF resistance by extending IGF1R half-life and activation in lung cancer.  EXPERIMENTAL AND MOLECULAR MEDICINE.  1,  1
  • (2023)  3D hepatic organoid production from human pluripotent stem cells.  DIFFERENTIATION.  135,  135
  • (2023)  Cell-permeable peptide nucleic acid antisense oligonucleotide platform targeting human betacoronaviruses.  FRONTIERS IN MICROBIOLOGY.  14,  1
  • (2023)  The SARS-CoV-2 spike protein induces lung cancer migration and invasion in a TLR2-dependent manner.  CANCER COMMUNICATIONS.  3,  4
  • (2022)  Paraoxonase-2 contributes to promoting lipid metabolism and mitochondrial function via autophagy activation.  SCIENTIFIC REPORTS.  12,  1
  • (2022)  Dysregulation of Liver Regeneration by Hepatitis B Virus Infection: Impact on Development of Hepatocellular Carcinoma.  CANCERS.  14,  15
  • (2022)  Susceptibility of Drug Resistant Hepatitis B Virus Mutants to Besifovir.  BIOMEDICINES.  10,  7
  • (2022)  The Roles of Ubiquitination in Pathogenesis of Influenza Virus Infection.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  23,  9
  • (2022)  Identification and Characterization of Besifovir-Resistant Hepatitis B Virus Isolated from a Chronic Hepatitis B Patient.  BIOMEDICINES.  10,  2
  • (2022)  Interaction between the Hepatitis B Virus and Cellular FLIP Variants in Viral Replication and the Innate Immune System.  VIRUSES-BASEL.  14,  2
  • (2021)  Hepatocyte Growth Factor-Dependent Antiviral Activity of Activated cdc42-Associated Kinase 1 Against Hepatitis B Virus.  FRONTIERS IN MICROBIOLOGY.  12,  1
  • (2021)  Besifovir therapy improves hepatic histology and reduces covalently closed circular DNA in chronic hepatitis B patients.  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY.  37,  2
  • (2021)  Distinctive HBV Replication Capacity and Susceptibility to Tenofovir Induced by a Polymerase Point Mutation in Hepatoma Cell Lines and Primary Human Hepatocytes.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  22,  4
  • (2021)  Continuing besifovir dipivoxil maleate versus switching from tenofovir disoproxil fumarate for treatment of chronic hepatitis B: Results of 192-week phase 3 trial.  CLINICAL AND MOLECULAR HEPATOLOGY.  27,  2
  • (2020)  Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system.  STEM CELL RESEARCH.  48,  48
  • (2020)  Entecavir-resistant hepatitis B virus decreases surface antigenicity: A full genome and functional characterization.  LIVER INTERNATIONAL.  40,  7
  • (2020)  Suppression of Hepatocyte Nuclear Factor 4 alpha by Long-term Infection of Hepatitis B Virus Contributes to Tumor Cell Proliferation.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  21,  3
  • (2019)  PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway (vol 10, 3185, 2019).  NATURE COMMUNICATIONS.  10,  1
  • (2019)  Co-degradation of interferon signaling factor DDX3 by PB1-F2 as a basis for high virulence of 1918 pandemic influenza.  EMBO JOURNAL.  38,  10

특허/프로그램

  • B형 간염 바이러스에서의 c-FLIP 단백질의 용도.  10-2018-0028015.  20200302.  대한민국
  • 약제 내성 B형 간염 바이러스의 검출 방법.  10-2018-0028014.  20200302.  대한민국

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